This two-day conference focuses on translational aspects of addiction research among chemists, biologists, and behavioral scientists. The diversity of participants and attendees at this meeting (undergraduate students to senior faculty, chemists to psychiatrists) provides a unique venue for cross-fertilization among different disciplines and in so doing promotes new and innovative approaches to medications development in addictions biology. The meeting provides a stimulating environment for young scientists who are strongly encouraged to present their work and interact with senior scientists. Friday Evening 3/2 Opening Reception on the San Antonio River Walk Saturday 3/3 Plenary symposium: “Relapse to drug taking: focus on corticotropin-releasing factor” Plenary Speakers: Dr. Yavin Shaham (NIH, NIDA) Dr. Eric Zorrilla (The Scripps Research Institute) Dr. Markus Heilig (NIH, NIAAA) Dr. Harriet de Wit (University of Chicago) Special Plenary Lecture - Dr. Phil Skolnick (NIH, NIDA) : "Developing medications to treat substance use disorders: why haven’t we been more successful?" Student Oral Communications Poster Session Dinner and After Dinner Speaker - Dr. John Grabowski (University of Minnesota) : "Harm reduction: substitution pharmacotherapy for substance use disorders 'I want a new drug'” Sunday Morning 3/4 Open Oral Communications Special Lecture - Dr. David Nichols (Purdue University) : "Multidisciplinary approaches to the study of the 5-HT2A receptor" Lunch and Adjournment